1932

Abstract

High-throughput genomic sequencing is rapidly changing the field of phylogenetics by decreasing the cost and increasing the quantity and rate of data collection by several orders of magnitude. This deluge of data is exerting tremendous pressure on downstream data-analysis methods providing new opportunities for method development. In this review, we present () recent advances in laboratory methods for collection of high-throughput phylogenetic data and () challenges and constraints for phylogenetic analysis of these data. We compare the merits of multiple laboratory approaches, compare methods of data analysis, and offer recommendations for the most promising protocols and data-analysis workflows currently available for phylogenetics. We also discuss several strategies for increasing accuracy, with an emphasis on locus selection and proper model choice.

Loading

Article metrics loading...

/content/journals/10.1146/annurev-ecolsys-110512-135822
2013-11-23
2024-10-07
Loading full text...

Full text loading...

/content/journals/10.1146/annurev-ecolsys-110512-135822
Loading
/content/journals/10.1146/annurev-ecolsys-110512-135822
Loading

Data & Media loading...

Supplementary Data

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error