1932

Abstract

Inhalation of the toxic smoke produced by combusting tobacco products, primarily cigarettes, is the overwhelming cause of tobacco-related disease and death in the United States and globally. A diverse class of alternative nicotine delivery systems (ANDS) has recently been developed that do not combust tobacco and are substantially less harmful than cigarettes. ANDS have the potential to disrupt the 120-year dominance of the cigarette and challenge the field on how the tobacco pandemic could be reversed if nicotine is decoupled from lethal inhaled smoke. ANDS may provide a means to compete with, and even replace, combusted cigarette use, saving more lives more rapidly than previously possible. On the basis of the scientific evidence on ANDS, we explore benefits and harms to public health to guide practice, policy, and regulation. A reframing of societal nicotine use through the lens of harm minimization is an extraordinary opportunity to enhance the impact of tobacco control efforts.

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2018-04-01
2024-07-15
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Literature Cited

  1. Abrams DB. 1.  2014. Potential and pitfalls of e-cigarettes—reply. JAMA 3111922–23 [Google Scholar]
  2. Abrams DB. 2.  2014. Promise and peril of e-cigarettes: Can disruptive technology make cigarettes obsolete?. JAMA 311135–36 [Google Scholar]
  3. Abrams DB, Niaura R. 3.  2015. The importance of science-informed policy and what the data really tell us about e-cigarettes. Isr. J. Health Policy Res 422 [Google Scholar]
  4. Adriaens K, Van Gucht D, Declerck P, Baeyens F. 4.  2014. Effectiveness of the electronic cigarette: an eight-week Flemish study with six-month follow-up on smoking reduction, craving and experienced benefits and complaints. Int. J. Environ. Res. Public Health 1111220–48 [Google Scholar]
  5. Babb S, Malarcher A, Schauer G, Asman K, Jamal A. 5.  2017. Quitting smoking among adults—United States, 2000–2015. MMWR 651457–64 [Google Scholar]
  6. Barrington-Trimis JL, Urman R, Berhane K, Unger JB, Cruz TB. 6.  et al. 2016. E-cigarettes and future cigarette use. Pediatrics 138e20160379 [Google Scholar]
  7. Bates C. 7.  2017. Rethinking nicotine: implications for U.S. federal tobacco policy. Discuss. Pap., Counterfactual London: https://www.clivebates.com/documents/FDAReformJune2017.pdf [Google Scholar]
  8. Bauld L, MacKintosh AM, Ford A, McNeill A. 8.  2016. E-cigarette uptake amongst UK youth: experimentation, but little or no regular use in nonsmokers. Nicotine Tob. Res. 18102–3 [Google Scholar]
  9. Benowitz NL, Donny EC, Hatsukami DK. 9.  2017. Reduced nicotine content cigarettes, e-cigarettes and the cigarette end game. Addiction 1126–7 [Google Scholar]
  10. Benowitz NL, Fraiman JB. 10.  2017. Cardiovascular effects of electronic cigarettes. Nat. Rev. Cardiol. 14447–56 [Google Scholar]
  11. Biener L, Hargraves JL. 11.  2015. A longitudinal study of electronic cigarette use among a population-based sample of adult smokers: association with smoking cessation and motivation to quit. Nicotine Tob. Res. 17127–33 [Google Scholar]
  12. Brandt AM. 12.  2007. The Cigarette Century: The Rise, Fall, and Deadly Persistence of the Product That Defined America New York: Basic Books [Google Scholar]
  13. Britton J, Bogdanovica I, McNeill A, Bauld L. 13.  2016. Commentary on WHO Report on electronic nicotine delivery systems and electronic non-nicotine delivery systems UK Cent. Tob. Alcohol Stud Nottingham, UK: http://ukctas.net/pdfs/UKCTAS-response-to-WHO-ENDS-report-26.10.2016.pdf [Google Scholar]
  14. Brose LS, Brown J, Hitchman SC, McNeill A. 14.  2015. Perceived relative harm of electronic cigarettes over time and impact on subsequent use. A survey with 1-year and 2-year follow-ups. Drug Alcohol. Depend. 157106–11 [Google Scholar]
  15. Brose LS, Hitchman SC, Brown J, West R, McNeill A. 15.  2015. Is the use of electronic cigarettes while smoking associated with smoking cessation attempts, cessation and reduced cigarette consumption? A survey with a 1-year follow-up. Addiction 1101160–68 [Google Scholar]
  16. Bullen C, Howe C, Laugesen M, McRobbie H, Parag V. 16.  et al. 2013. Electronic cigarettes for smoking cessation: a randomised controlled trial. Lancet 3821629–37 [Google Scholar]
  17. 17. Can. Paediatr. Soc. 2008. Harm reduction: an approach to reducing risky health behaviours in adolescents. Paediatr. Child Health 1353–56 [Google Scholar]
  18. Caponnetto P, Campagna D, Cibella F, Morjaria JB, Caruso M. 18.  et al. 2013. EffiCiency and Safety of an eLectronic cigAreTte (ECLAT) as tobacco cigarettes substitute: a prospective 12-month randomized control design study. PLOS ONE 8e66317 [Google Scholar]
  19. Caraballo RS, Shafer PR, Patel D, Davis KC, McAfee TA. 19.  2017. Quit methods used by US adult cigarette smokers, 2014–2016. Prev. Chronic Dis. 14E32 [Google Scholar]
  20. 20. CDC (Cent. Dis. Control Prev.). 2014. Best Practices for Comprehensive Tobacco Control Programs—2014 Atlanta: US Dep. Health Hum. Serv., Cent. Dis. Control Prev., Natl. Cent. Chronic Dis. Prev. Health Promot., Off. Smok. Health [Google Scholar]
  21. 21. CDC (Cent. Dis. Control Prev.). 2016. Early Release of Selected Estimates Based on Data from the National Health Interview Survey, January–March 2016 Atlanta: US Dep. Health Hum. Serv., Cent. Dis. Control Prev., Natl. Cent. Health Stat. [Google Scholar]
  22. Chaloupka FJ, Sweanor D, Warner KE. 22.  2015. Differential taxes for differential risks—toward reduced harm from nicotine-yielding products. N. Engl. J. Med. 373594–97 [Google Scholar]
  23. Cobb CO, Villanti AC, Graham AL, Pearson JL, Glasser AM. 23.  et al. 2015. Markov modeling to estimate the population impact of emerging tobacco products: a proof-of-concept study. Tobacco Reg. Sci. 12121–41 [Google Scholar]
  24. Cobb NK, Abrams DB. 24.  2014. The FDA, e-cigarettes, and the demise of combusted tobacco. N. Engl. J. Med. 3711469–71 [Google Scholar]
  25. Collins LK, Villanti AC, Pearson JL, Glasser AM, Johnson AL. 25.  et al. 2017. Frequency of youth e-cigarette, tobacco, and poly-use in the United States, 2015: Update to Villanti et al., “Frequency of Youth E-Cigarette and Tobacco Use Patterns in the United States: Measurement Precision Is Critical to Inform Public Health. .” Nicotine Tob. Res. 191253–54 [Google Scholar]
  26. Delnevo CD, Giovenco DP, Steinberg MB, Villanti AC, Pearson JL. 26.  et al. 2016. Patterns of electronic cigarette use among adults in the United States. Nicotine Tob. Res. 18715–19 [Google Scholar]
  27. Donny EC, Denlinger RL, Tidey JW, Koopmeiners JS, Benowitz NL. 27.  et al. 2015. Randomized trial of reduced-nicotine standards for cigarettes. N. Engl. J. Med. 3731340–49 [Google Scholar]
  28. Fairchild A, Niaura R, Abrams D. 28.  2017. America needs a candid smoking control champion. The Hill Nov. 13. http://thehill.com/opinion/healthcare/360111-america-needs-a-candid-smoking-control-champion [Google Scholar]
  29. Fagerstrom K, Etter JF, Unger JB. 29.  2015. E-cigarettes: a disruptive technology that revolutionizes our field?. Nicotine Tob. Res. 17125–26 [Google Scholar]
  30. Fagerstrom KO, Bridgman K. 30.  2014. Tobacco harm reduction: the need for new products that can compete with cigarettes. Addict. Behav. 39507–11 [Google Scholar]
  31. Farsalinos KE, Poulas K, Voudris V, Le Houezec J. 31.  2016. Electronic cigarette use in the European Union: analysis of a representative sample of 27,460 Europeans from 28 countries Addiction. 111112032–40
  32. Farsalinos KE, Poulas K, Voudris V, Le Houezec J. 32.  2017. Prevalence and correlates of current daily use of electronic cigarettes in the European Union: analysis of the 2014 Eurobarometer survey. Intern. Emerg. Med. 12757–63 [Google Scholar]
  33. Farsalinos KE, Romagna G, Tsiapras D, Kyrzopoulos S, Spyrou A, Voudris V. 33.  2013. Impact of flavour variability on electronic cigarette use experience: an Internet survey. Int. J. Environ. Res. Public Health 107272–82 [Google Scholar]
  34. Farsalinos KE, Voudris V, Poulas K. 34.  2015. E-cigarettes generate high levels of aldehydes only in ‘dry puff’ conditions. Addiction 1101352–56 [Google Scholar]
  35. Feirman SP, Glasser AM, Rose S, Niaura R, Abrams DB. 35.  et al. 2017. Computational models used to assess US tobacco control policies. Nicotine Tob. Res. 191257–67 [Google Scholar]
  36. Fiore MC, Schroeder SA, Baker TB. 36.  2014. Smoke, the chief killer—strategies for targeting combustible tobacco use. N. Engl. J. Med. 370297–99 [Google Scholar]
  37. Friedman AS. 37.  2015. How does electronic cigarette access affect adolescent smoking?. J. Health Econ. 44300–8 [Google Scholar]
  38. Fucito LM, Bars MP, Forray A, Rojewski AM, Shiffman S. 38.  et al. 2014. Addressing the evidence for FDA nicotine replacement therapy label changes: a policy statement of the Association for the Treatment of Tobacco Use and Dependence and the Society for Research on Nicotine and Tobacco. Nicotine Tob. Res. 16909–14 [Google Scholar]
  39. Giovenco DP, Delnevo CD. 39.  2018. Prevalence of smoking cessation by electronic cigarette use status in a national sample of recent smokers. Addict Behav 76129–34 [Google Scholar]
  40. Gitchell JG, Shiffman S, Sembower MA. 40.  2017. Trends in serious quit attempts in the United States, 2009–14. Addiction 112897–900 [Google Scholar]
  41. Glasser AM, Collins L, Pearson JL, Abudayyeh H, Niaura RS. 41.  et al. 2017. Overview of electronic nicotine delivery systems: a systematic review. Am. J. Prev. Med. 52e33–66 [Google Scholar]
  42. Goniewicz ML, Gawron M, Smith DM, Peng M, Jacob P 3rd, Benowitz NL. 42.  2017. Exposure to nicotine and selected toxicants in cigarette smokers who switched to electronic cigarettes: a longitudinal within-subjects observational study. Nicotine Tob. Res. 19160–67 [Google Scholar]
  43. Goniewicz ML, Knysak J, Gawron M, Kosmider L, Sobczak A. 43.  et al. 2014. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob. Control 23133–39 [Google Scholar]
  44. Gottlieb S, Zeller M. 44.  2017. A nicotine-focused framework for public health. N Engl. J. Med. 377121111–14 [Google Scholar]
  45. Hammond D, McDonald PW, Fong GT, Borland R. 45.  2004. Do smokers know how to quit? Knowledge and perceived effectiveness of cessation assistance as predictors of cessation behaviour. Addiction 991042–48 [Google Scholar]
  46. 46. Harm Reduct. Int. 2017. What is harm reduction? Harm Reduct. Int London: https://www.hri.global/what-is-harm-reduction [Google Scholar]
  47. Hartmann-Boyce J, McRobbie H, Bullen C, Begh R, Stead LF, Hajek P. 47.  2016. Electronic cigarettes for smoking cessation. Cochrane Database Syst. Rev9CD010216 [Google Scholar]
  48. Hecht SS, Carmella SG, Kotandeniya D, Pillsbury ME, Chen M. 48.  et al. 2015. Evaluation of toxicant and carcinogen metabolites in the urine of e-cigarette users versus cigarette smokers. Nicotine Tob. Res. 17704–9 [Google Scholar]
  49. Heishman SJ, Kleykamp BA, Singleton EG. 49.  2010. Meta-analysis of the acute effects of nicotine and smoking on human performance. Psychopharmacology 210453–69 [Google Scholar]
  50. Higgins JPT, Green S. 50.  2008. Cochrane Handbook for Systematic Reviews of Interventions, Cochrane Book Series. . West Sussex, UK: Wiley-Blackwell
  51. Hitchman SC, Brose LS, Brown J, Robson D, McNeill A. 51.  2015. Associations between e-cigarette type, frequency of use, and quitting smoking: findings from a longitudinal online panel survey in Great Britain. Nicotine Tob. Res. 171187–94 [Google Scholar]
  52. Huerta TR, Walker DM, Mullen D, Johnson TJ, Ford EW. 52.  2017. Trends in e-cigarette awareness and perceived harmfulness in the U.S. Am. J. Prev. Med. 52339–46 [Google Scholar]
  53. Huh J, Leventhal AM. 53.  2016. Progression of poly-tobacco product use patterns in adolescents. Am. J. Prev. Med. 51513–17 [Google Scholar]
  54. 54. IOM (Inst. Med.). 2007. Ending the Tobacco Problem: A Blueprint for the Nation Washington, DC: Natl. Acad. Press [Google Scholar]
  55. Jamal A, Gentzke A, Hu SS, Cullen KA, Apelberg BJ. 55.  et al. 2017. Tobacco use among middle and high school students—United States, 2011–2016. MMWR 66597–603 [Google Scholar]
  56. Kalkhoran S, Glantz SA. 56.  2016. E-cigarettes and smoking cessation in real-world and clinical settings: a systematic review and meta-analysis. Lancet Respir. Med. 4116–28 [Google Scholar]
  57. Kozlowski LT, Abrams DB. 57.  2016. Obsolete tobacco control themes can be hazardous to public health: the need for updating views on absolute product risks and harm reduction. BMC Public Health 16432 [Google Scholar]
  58. Kozlowski LT, Edwards BQ. 58.  2005. “Not safe” is not enough: Smokers have a right to know more than there is no safe tobacco product. Tob. Control. 14Suppl. 2ii3–7 [Google Scholar]
  59. Kozlowski LT, Goldberg ME, Yost BA, White EL, Sweeney CT, Pillitteri JL. 59.  1998. Smokers' misperceptions of light and ultra-light cigarettes may keep them smoking. Am. J. Prev. Med. 159–16 [Google Scholar]
  60. Kozlowski LT, O'Connor RJ. 60.  2003. Apply federal research rules on deception to misleading health information: an example on smokeless tobacco and cigarettes. Public Health Rep 118187–92 [Google Scholar]
  61. Kozlowski LT, Strasser AA, Giovino GA, Erickson PA, Terza JV. 61.  2001. Applying the risk/use equilibrium: use medicinal nicotine now for harm reduction. Tob. Control. 10201–3 [Google Scholar]
  62. Kozlowski LT, Sweanor D. 62.  2016. Withholding differential risk information on legal consumer nicotine/tobacco products: the public health ethics of health information quarantines. Int. J. Drug Policy 3217–23 [Google Scholar]
  63. Kozlowski LT, Warner KE. 63.  2017. Adolescents and e-cigarettes: Objects of concern may appear larger than they are. Drug Alcohol. Depend. 174209–14 [Google Scholar]
  64. Lee PN. 64.  2011. Summary of the epidemiological evidence relating snus to health. Regul. Toxicol. Pharmacol. 59197–214 [Google Scholar]
  65. Lee PN. 65.  2013. Epidemiological evidence relating snus to health—an updated review based on recent publications. Harm. Reduct. J. 1036 [Google Scholar]
  66. Lee PN, Hamling J. 66.  2009. Systematic review of the relation between smokeless tobacco and cancer in Europe and North America. BMC Med 736 [Google Scholar]
  67. Leventhal AM, Stone MD, Andrabi N, Barrington-Trimis J, Strong DR. 67.  et al. 2016. Association of e-cigarette vaping and progression to heavier patterns of cigarette smoking. JAMA 3161918–20 [Google Scholar]
  68. Leventhal AM, Strong DR, Kirkpatrick MG, Unger JB, Sussman S. 68.  et al. 2015. Association of electronic cigarette use with initiation of combustible tobacco product smoking in early adolescence. JAMA 314700–7 [Google Scholar]
  69. Levy DT, Borland R, Lindblom EN, Goniewicz ML, Meza R. 69.  et al. 2017. Potential deaths averted in USA by replacing cigarettes with e-cigarettes. Tob Control 2718–25 [Google Scholar]
  70. Levy DT, Borland R, Villanti AC, Niaura R, Yuan Z. 70.  et al. 2017. The application of a decision-theoretic model to estimate the public health impact of vaporized nicotine product initiation in the United States. Nicotine Tob. Res. 19149–59 [Google Scholar]
  71. Levy DT, Cummings KM, Villanti AC, Niaura R, Abrams DB. 71.  et al. 2017. A framework for evaluating the public health impact of e-cigarettes and other vaporized nicotine products. Addiction 11218–17 [Google Scholar]
  72. Levy DT, Yuan Z, Luo Y, Abrams DB. 72.  2017. The relationship of e-cigarette use to cigarette quit attempts and cessation: insights from a large, nationally representative U.S. survey. Nicotine Tob. Res. https://doi.org/10.1093/ntr/ntx166 [Crossref] [Google Scholar]
  73. Liu G, Wasserman E, Kong L, Foulds J. 73.  2017. A comparison of nicotine dependence among exclusive E-cigarette and cigarette users in the PATH study. Prev. Med. 10486–91 [Google Scholar]
  74. Majeed BA, Weaver SR, Gregory KR, Whitney CF, Slovic P. 74.  et al. 2017. Changing perceptions of harm of e-cigarettes among U.S. adults, 2012–2015. Am. J. Prev. Med. 52331–38 [Google Scholar]
  75. Manzoli L, Flacco ME, Fiore M, La Vecchia C, Marzuillo C. 75.  et al. 2015. Electronic cigarettes efficacy and safety at 12 months: cohort study. PLOS ONE 10e0129443 [Google Scholar]
  76. Marlatt GA, Witkiewitz K. 76.  2010. Update on harm-reduction policy and intervention research. Annu. Rev. Clin. Psychol. 6591–606 [Google Scholar]
  77. McNeill A, Brose LS, Calder R, Hitchman S, Hajek P, McRobbie H. 77.  2015. E-Cigarettes: An Evidence Update—A Report Commissioned by Public Health England London: Public Health England [Google Scholar]
  78. McRobbie H, Bullen C, Hartmann-Boyce J, Hajek P. 78.  2014. Electronic cigarettes for smoking cessation and reduction. Cochrane Database Syst. Rev. 12CD010216 [Google Scholar]
  79. Miech R, Patrick ME, O'Malley PM, Johnston LD. 79.  2017. E-cigarette use as a predictor of cigarette smoking: results from a 1-year follow-up of a national sample of 12th grade students. Tob. Control https://doi.org/10.1136/tobaccocontrol-2016-053291 [Crossref] [Google Scholar]
  80. Miech R, Patrick ME, O'Malley PM, Johnston LD. 80.  2017. What are kids vaping? Results from a national survey of US adolescents. Tob. Control. 26386–91 [Google Scholar]
  81. 81. Monit. Future—Univ. Mich. 2017. Table 1: Trends in annual and 30-day prevalence of use of other tobacco products for grades 8, 10, and 12 Univ. Mich Ann Arbor: http://www.monitoringthefuture.org/data/16data/16cigtbl1.pdf [Google Scholar]
  82. 82. Monit. Future—Univ. Mich. 2017. Table 2: Trends in prevalence of use of cigarettes in grades, 8, 10, and 12 Univ. Mich Ann Arbor: http://www.monitoringthefuture.org/data/16data/16cigtbl2.pdf [Google Scholar]
  83. 83. NCI (Natl. Cancer Inst.). 2015. Compared to smoking cigarettes, would you say that electronic cigarettes are… Health Inf. Natl. Trends Survey (HINTS) Response, NCI, Natl. Inst. Health Bethesda, MD: https://hints.cancer.gov/question-details.aspx?PK_Cycle=8&qid=1282 [Google Scholar]
  84. 84. NCI (Natl. Cancer Inst.). 2017. Dispelling myths about nicotine replacement therapy Fact Sheet, NCI, Natl. Inst. Health Bethesda, MD: http://smokefree.gov/sites/default/files/pdf/mythsaboutNRTfactsheet.pdf [Google Scholar]
  85. Niaura R. 85.  2016. Re-thinking nicotine and its effects Schroeder Inst. Tob. Res. Policy Stud., Truth Initiat Washington, DC: https://truthinitiative.org/sites/default/files/ReThinking-Nicotine.pdf [Google Scholar]
  86. Niaura RS, Glynn TJ, Abrams DB. 86.  2014. Youth experimentation with e-cigarettes: another interpretation of the data. JAMA Pediatr 312641–42 [Google Scholar]
  87. Nocera J. 87.  2015. Can e-cigarettes save lives?. New York Times Oct. 16. https://www.nytimes.com/2015/10/17/opinion/can-e-cigarettes-save-lives.html?_r=0 [Google Scholar]
  88. Nocera J. 88.  2017. When public health and Big Tobacco align. Bloomberg View March 9. https://www.bloomberg.com/view/articles/2017-03-09/when-public-health-and-big-tobacco-align [Google Scholar]
  89. Nutt DJ, Phillips LD, Balfour D, Curran HV, Dockrell M. 89.  et al. 2014. Estimating the harms of nicotine-containing products using the MCDA approach. Eur. Addict. Res. 20218–25 [Google Scholar]
  90. Nutt DJ, Phillips LD, Balfour D, Curran HV, Dockrell M. 90.  et al. 2016. E-cigarettes are less harmful than smoking. Lancet 3871160–62 [Google Scholar]
  91. O'Brien B, Knight-West O, Walker N, Parag V, Bullen C. 91.  2015. E-cigarettes versus NRT for smoking reduction or cessation in people with mental illness: secondary analysis of data from the ASCEND trial. Tob. Induc. Dis. 135 [Google Scholar]
  92. O'Leary R, MacDonald M, Stockwell T, Reist D. 92.  2017. Clearing the Air: A Systematic Review on the Harms and Benefits of E-Cigarettes and Vapour Devices Victoria, BC, Can: Univ. Vic. Cent. Addict. Res. BC [Google Scholar]
  93. Parks SH, Duncan DT, Shahawy OE, Lee L, Shearston JA. 93.  et al. 2017. Characteristics of adults who switched from cigarette smoking to e-cigarettes. Am. J. Prev. Med. 535652–60 [Google Scholar]
  94. Pesko MF, Currie JM. 94.  2016. The effect of e-cigarette minimum legal sale age laws on traditional cigarette use and birth outcomes among pregnant teenagers NBER Work. Pap. 22792 [Google Scholar]
  95. Pesko MF, Hughes JM, Faisal FS. 95.  2016. The influence of electronic cigarette age purchasing restrictions on adolescent tobacco and marijuana use. Prev. Med. 87207–12 [Google Scholar]
  96. Polosa R, Campagna D, Sands MF. 96.  2016. Counseling patients with asthma and allergy about electronic cigarettes: an evidence-based approach. Ann. Allergy Asthma Immunol. 116106–11 [Google Scholar]
  97. Polosa R, Morjaria J, Caponnetto P, Caruso M, Strano S. 97.  et al. 2014. Effect of smoking abstinence and reduction in asthmatic smokers switching to electronic cigarettes: evidence for harm reversal. Int. J. Environ. Res. Public Health 114965–77 [Google Scholar]
  98. Polosa R, Morjaria JB, Caponnetto P, Caruso M, Campagna D. 98.  et al. 2016. Persisting long term benefits of smoking abstinence and reduction in asthmatic smokers who have switched to electronic cigarettes. Discov. Med. 2199–108 [Google Scholar]
  99. Primack BA, Soneji S, Stoolmiller M, Fine MJ, Sargent JD. 99.  2015. Progression to traditional cigarette smoking after electronic cigarette use among US adolescents and young adults. JAMA Pediatr 1691018–23 [Google Scholar]
  100. Proctor RN. 100.  2011. Golden Holocaust: Origins of the Cigarette Catastrophe and the Case for Abolition Oakland: Univ. Calif. Press [Google Scholar]
  101. 101. Reuters. 2016. Philip Morris CEO sketches a future where the company doesn't sell cigarettes. Fortune Nov. 30. http://fortune.com/2016/11/30/philip-morris-ceo-future-without-cigarettes/ [Google Scholar]
  102. Rose JE, Turner JE, Murugesan T, Behm FM, Laugesen M. 102.  2010. Pulmonary delivery of nicotine pyruvate: sensory and pharmacokinetic characteristics. Exp. Clin. Psychopharmacol. 18385–94 [Google Scholar]
  103. 103. RPC (R. Coll. Phys.). 2016. Nicotine Without Smoke: Tobacco Harm Reduction London: RPC https://www.rcplondon.ac.uk/projects/outputs/nicotine-without-smoke-tobacco-harm-reduction-0 [Google Scholar]
  104. Russell C, McKeganey N. 104.  2017. Patterns of cigarette smoking and e-cigarette use among 20,676 adult frequent e-cigarette users in the United States Cent. Subst. Use Res Glasgow, UK: http://substanceuseresearch.org/usvaperssurvey [Google Scholar]
  105. Russell MA. 105.  1976. Low-tar medium-nicotine cigarettes: a new approach to safer smoking. BMJ 11430–33 [Google Scholar]
  106. Smiley SL, DeAtley T, Rubin LF, Harvey E, Kierstead EC. 106.  et al. 2017. Early subjective sensory experiences with “cigalike” e-cigarettes among African American menthol smokers: a qualitative study. Nicotine Tob. Res. https://doi.org/10.1093/ntr/ntx102 [Crossref] [Google Scholar]
  107. Spindle TR, Hiler MM, Cooke ME, Eissenberg T, Kendler KS, Dick DM. 107.  2017. Electronic cigarette use and uptake of cigarette smoking: a longitudinal examination of U.S. college students. Addict. Behav. 6766–72 [Google Scholar]
  108. Steinberg L. 108.  2007. Risk taking in adolescence: new perspectives from brain and behavioral science. Curr. Dir. Psychol. Sci. 1655–59 [Google Scholar]
  109. Strong DR, Pearson J, Ehlke S, Kirchner TR, Abrams D. 109.  et al. 2017. Indicators of dependence for different types of tobacco product users: descriptive findings from wave 1 (2013–2014) of the Population Assessment of Tobacco and Health (PATH) study. Drug Alcohol. Depend. 178257–66 [Google Scholar]
  110. Talati A, Keyes KM, Hasin DS. 110.  2016. Changing relationships between smoking and psychiatric disorders across twentieth century birth cohorts: clinical and research implications. Mol. Psychiatry 21464–71 [Google Scholar]
  111. 111. Tob. Prod. Sci. Advis. Comm. 2011. Menthol Cigarettes and Public Health: Review of the Scientific Evidence and Recommendations Rockville, MD: US Food Drug Adm., Cent. Tob. Prod. [Google Scholar]
  112. 112. Tob. Use Depend. Guidel. Panel. 2008. Treating Tobacco Use and Dependence: 2008 Update Rockville, MD: US Dep. Health Hum. Serv. [Google Scholar]
  113. 113. Trefis Team. 2016. FDA approval for iQOS to be a game changer for Altria. Forbes Dec. 30. https://www.forbes.com/sites/greatspeculations/2016/12/30/fda-approval-for-iqos-to-be-a-game-changer-for-altria/#385ca26b1a36 [Google Scholar]
  114. Tseng TY, Ostroff JS, Campo A, Gerard M, Kirchner T. 114.  et al. 2016. A randomized trial comparing the effect of nicotine versus placebo electronic cigarettes on smoking reduction among young adult smokers. Nicotine Tob. Res. 181937–43 [Google Scholar]
  115. 115. US Dep. Health Hum. Serv. 2001. Workshop summary: scientific evidence on condom effectiveness for sexually transmitted disease (STD) prevention Workshop Summ., July 20, Natl. Inst. Allergy Infect. Dis., Natl. Inst. Health, Dep. Health Hum. Serv Herndon, VA: https://chastityproject.com/wp/wp-content/uploads/2013/05/NIH-Condom-Report.pdf [Google Scholar]
  116. 116. US Dep. Health Hum. Serv. 2010. How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease: A Report of the Surgeon General Atlanta: US Dep. Health Hum. Serv., Cent. Dis. Control Prev., Natl. Cent. Chronic Dis. Prev. Health Promot., Off. Smok. Health https://www.ncbi.nlm.nih.gov/books/NBK53017/ [Google Scholar]
  117. 117. US Dep. Health Hum. Serv. 2014. The Health Consequences of Smoking—50 Years of Progress: A Report of the Surgeon General Atlanta: US Dep. Health Hum. Serv., Cent. Dis. Control Prev., Natl. Cent. Chronic Dis. Prev. Health Promot., Off. Smok. Health https://www.surgeongeneral.gov/library/reports/50-years-of-progress/full-report.pdf [Google Scholar]
  118. 118. US Dep. Health Hum. Serv. 2016. E-Cigarette Use Among Youth and Young Adults: A Report of the Surgeon General Atlanta: US Dep. Health Hum. Serv., Cent. Dis. Control Prev., Natl. Cent. Chronic Dis. Prev. Health Promot., Off. Smok. Health https://e-cigarettes.surgeongeneral.gov/documents/2016_sgr_full_report_non-508.pdf [Google Scholar]
  119. 119. US Dep. Health Hum. Serv. 2017. FDA announces comprehensive regulatory plan to shift trajectory of tobacco-related disease, death News Release, July 28. https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm568923.htm [Google Scholar]
  120. 120. US FDA (Food Drug Adm.). 2009. Division A—Family Smoking Prevention and Tobacco Control Act Public Law 111–31, Jun 22. https://www.gpo.gov/fdsys/pkg/PLAW-111publ31/pdf/PLAW-111publ31.pdf [Google Scholar]
  121. 121. US FDA (Food Drug Adm.). 2012. Harmful and potentially harmful constituents in tobacco products and tobacco smoke; established list. Fed. Regist. 7720034–37 https://www.federalregister.gov/documents/2012/04/03/2012-7727/harmful-and-potentially-harmful-constituents-in-tobacco-products-and-tobacco-smoke-established-list [Google Scholar]
  122. 122. US FDA (Food Drug Adm.). 2013. Nicotine replacement therapy labels may change April 1, US FDA Silver Spring, MD: https://www.integration.samhsa.gov/health-wellness/NRT_Label_Change_0413.pdf [Google Scholar]
  123. Vanyukov MM, Tarter RE, Kirillova GP, Kirisci L, Reynolds MD. 123.  et al. 2012. Common liability to addiction and “gateway hypothesis”: theoretical, empirical and evolutionary perspective. Drug Alcohol. Depend. 123Suppl. 1S3–17 [Google Scholar]
  124. Villanti AC, Giovino GA, Burns DM, Abrams DB. 124.  2013. Menthol cigarettes and mortality: keeping focus on the public health standard. Nicotine Tob. Res. 15617–18 [Google Scholar]
  125. Villanti AC, Johnson AL, Ambrose BK, Cummings KM, Stanton CA. 125.  et al. 2017. Flavored tobacco product use in youth and adults: findings from the first wave of the PATH study (2013–2014). Am. J. Prev. Med. 53139–51 [Google Scholar]
  126. Villanti AC, Feirman SP, Niaura RS, Pearson JL, Glasser AM. 126.  et al. 2017. How do we determine the impact of e-cigarettes on cigarette smoking cessation or reduction? Review and recommendations for answering the research question with scientific rigor. Addiction https://doi.org/10.1111/add.14020 [Crossref] [Google Scholar]
  127. Villanti AC, Pearson JL, Glasser AM, Johnson AL, Collins LK. 127.  et al. 2017. Frequency of youth e-cigarette and tobacco use patterns in the U.S.: measurement precision is critical to inform public health. Nicotine Tob. Res. 191345–50 [Google Scholar]
  128. Villanti AC, Vargyas EJ, Niaura RS, Beck SE, Pearson JL, Abrams DB. 128.  2011. Food and Drug Administration regulation of tobacco: integrating science, law, policy, and advocacy. Am. J. Public Health 1011160–62 [Google Scholar]
  129. Vlahov D, Robertson AM, Strathdee SA. 129.  2010. Prevention of HIV infection among injection drug users in resource-limited settings. Clin. Infect. Dis. 50Suppl. 3S114–21 [Google Scholar]
  130. Walton KM, Abrams DB, Bailey WC, Clark D, Connolly GN. 130.  et al. 2015. NIH electronic cigarette workshop: developing a research agenda. Nicotine Tob. Res. 17259–69 [Google Scholar]
  131. Warner K. 131.  2015. The remarkable decrease in cigarette smoking by American youth: further evidence. Prev. Med. Rep 2259–61 [Google Scholar]
  132. Warner KE. 132.  2013. An endgame for tobacco?. Tob. Control 22Suppl. 1i3–5 [Google Scholar]
  133. Warner KE. 133.  2016. Frequency of e-cigarette use and cigarette smoking by American students in 2014. Am. J. Prev. Med. 51179–84 [Google Scholar]
  134. West R, Hajek P, Foulds J, Nilsson F, May S, Meadows A. 134.  2000. A comparison of the abuse liability and dependence potential of nicotine patch, gum, spray and inhaler. Psychopharmacology 149198–202 [Google Scholar]
  135. West R, Shahab L, Brown J. 135.  2016. Estimating the population impact of e-cigarettes on smoking cessation in England. Addiction 1111118–19 [Google Scholar]
  136. 136. WHO (World Health Organ.). 2008. WHO Report on the Global Tobacco Epidemic, 2008: The MPOWER Package Geneva: WHO [Google Scholar]
  137. 137. WHO (World Health Organ.). 2011. WHO Report on the Global Tobacco Epidemic, 2011: Warning About the Dangers of Tobacco Geneva: WHO [Google Scholar]
  138. 138. WHO (World Health Organ.). 2016. HIV/AIDS: people who inject drugs WHO Geneva: http://www.who.int/hiv/topics/idu/en/ [Google Scholar]
  139. 139. WHO (World Health Organ.). 2017. Tobacco Updated May, Fact Sheet, WHO Geneva: http://www.who.int/mediacentre/factsheets/fs339/en/ [Google Scholar]
  140. Wills TA, Gibbons FX, Sargent JD, Schweitzer RJ. 140.  2016. How is the effect of adolescent e-cigarette use on smoking onset mediated: a longitudinal analysis. Psychol. Addict. Behav. 30876–86 [Google Scholar]
  141. Wills TA, Knight R, Sargent JD, Gibbons FX, Pagano I, Williams RJ. 141.  2017. Longitudinal study of e-cigarette use and onset of cigarette smoking among high school students in Hawaii. Tob. Control 2634–39 [Google Scholar]
  142. Wills TA, Sargent JD, Gibbons FX, Pagano I, Schweitzer R. 142.  2017. E-cigarette use is differentially related to smoking onset among lower risk adolescents. Tob. Control 26534–39 [Google Scholar]
  143. Yach D. 143.  2017. Foundation for a smoke-free world. Lancet 3901807–10 [Google Scholar]
  144. Zhu S-H, Zhuang Y-L, Wong S, Cummins SE, Tedeschi GJ. 144.  2017. E-cigarette use and associated changes in population smoking cessation: evidence from US current population surveys. BMJ 358j3262 [Google Scholar]
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