1932

Abstract

Abstract

The evolution of RNA sequence needs to satisfy three requirements: folding, structure, and function. Studies on folding during transcription are related directly to folding in the cell. Understanding RNA folding during transcription requires the elucidation of structure formation and structural changes of the RNA, and the consideration of intrinsic properties of the RNA polymerase and other proteins that interact with the RNA. This review summarizes the research progress in this area and outlines the enormous challenges facing this field. Significant advancement requires the development of new experimental methods and theoretical considerations in all aspects of transcription and RNA folding.

Loading

Article metrics loading...

/content/journals/10.1146/annurev.biophys.35.040405.102053
2006-06-09
2024-12-11
Loading full text...

Full text loading...

/content/journals/10.1146/annurev.biophys.35.040405.102053
Loading
/content/journals/10.1146/annurev.biophys.35.040405.102053
Loading

Data & Media loading...

  • Article Type: Review Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error