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Abstract

Airway smooth muscle plays a multifaceted role in the pathogenesis of asthma. We review the current understanding of the contribution of airway myocytes to airway inflammation, airway wall remodeling, and airflow obstruction in this prevalent disease syndrome. Together, these roles make airway smooth muscle an attractive target for asthma therapy.

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/content/journals/10.1146/annurev.pathmechdis.1.110304.100213
2008-02-28
2024-04-15
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  • Article Type: Review Article
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