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Annual Review of Animal Biosciences

Volume 10, 2022

Translating Basic Research to Animal Agriculture

Abstract

Procedures to maintain viability of mammalian gametes and embryos in vitro, including cryopreservation, have been exceedingly valuable for my research over the past 55 years. Keeping sperm viable in vitro enables artificial insemination, which, when combined with selective breeding, often is the most effective approach to making rapid genetic change in a population. Superovulation and embryo transfer constitute a parallel approach for amplifying reproduction of female mammals. More recent developments include sexing of semen, in vitro fertilization, cloning by nuclear transfer, and genetic modification of germline cells, tools that are enabled by artificial insemination and/or embryo transfer for implementation. I have been fortunate in being able to contribute to the development of many of the above techniques, and to use them for research and applications for improving animal agriculture. Others have built on this work to circumvent human infertility, assist reproduction of companion animals, and rescue endangered species. It also has been a privilege to teach, mentor, and be mentored in this area. Resulting worldwide friendships have enriched me personally and professionally.

Keyword(s): assisted reproduction, autobiography, biotechnology, embryo, in vitro, oocyte, sperm
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2022-02-15
2024-04-26
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Literature Cited

  1. 1. 
    Seidel GE Jr. 2019. Effects of transitions in North American animal agriculture on animal well-being: personal observations. Appl. Anim. Ethics Res. 1:41–65
     [Google Scholar]
  2. 2. 
    Seidel GE Jr., Whittier JC. 2015. Beef Species Symposium: beef production without mature cows. . J. Anim. Sci. 93:4244–51
     [Google Scholar]
  3. 3. 
    Brackett BG, Seidel GE Jr., Seidel SM. 1981. New Technologies in Animal Breeding Cambridge, UK: Academic
  4. 4. 
    Amann RP, Seidel GE Jr. 1982. Prospects for Sexing Mammalian Sperm Boulder: Colo. Assoc. Univ. Press
  5. 5. 
    Seidel GE Jr. 2009. Update on sexing mammalian sperm. Theriogenology 71:1–107
     [Google Scholar]
  6. 6. 
    Seidel GE Jr. 2015. Maintaining integrity of germline DNA: Individuals age, species do not. Reprod. Fertil. Dev. 27:865–71
     [Google Scholar]
  7. 7. 
    Seidel GE Jr. 2000. Reproductive biotechnology and “big” biological questions. Theriogenology 53:187–94
     [Google Scholar]
  8. 8. 
    Back DG, Pickett BW, Voss JL, Seidel GE Jr. 1974. Observations on the sexual behavior of nonlactating mares. J. Am. Vet. Med. Assoc. 165:717–20
     [Google Scholar]
  9. 9. 
    Polge C, Smith AU, Parker AS. 1949. Revival of spermatozoa after vitrification and dehydration at low temperatures. Nature 164:666
     [Google Scholar]
  10. 10. 
    Whittingham DG, Leibo SP, Mazur P. 1972. Survival of mouse embryos frozen to −196 degrees and −269 degrees C. Science 178:411–14
     [Google Scholar]
  11. 11. 
    Mazur P, Leibo SP, Seidel GE Jr. 2008. Cryopreservation of the germplasm of animals used in biological and medical research: importance, impact, status, and future directions. Biol. Reprod. 78:2–12
     [Google Scholar]
  12. 12. 
    Rall WF, Fahy GM. 1985. Ice-free cryopreservation of mouse embryos at −196 degrees C by vitrification. Nature 313:573–75
     [Google Scholar]
  13. 13. 
    Bowen RA, Reed ML, Schnieke A, Seidel GE Jr., Stacey A et al. 1994. Transgenic cattle from biopsied embryos: expression of c-ski in a transgenic calf. Biol. Reprod. 50:664–68
     [Google Scholar]
  14. 14. 
    Seidel GE Jr. 2020. GM farm animals: potential impact on biodiversity including ethical concerns. GMOs 19:277–85
     [Google Scholar]
  15. 15. 
    Bhartiya D, Anand S, Patel H, Parte S 2017. Making gametes from alternative sources of stem cells: past, present and future. Reprod. Biol. Endocrinol. 15:89
     [Google Scholar]
  16. 16. 
    Seidel GE Jr., Larson LL, Foote RH. 1971. Effects of age and gonadotropin treatment on superovulation in the calf. J. Anim. Sci. 33:617–22
     [Google Scholar]
  17. 17. 
    Seidel GE Jr., Larson LL, Spilman CH, Hahn J, Foote RH. 1971. Culture and transfer of calf ova. J. Dairy Sci. 54:923–26
     [Google Scholar]
  18. 18. 
    Spilman CH, Seidel GE Jr., Larson LL, Vukman GR, Foote RH. 1973. Progesterone, 20β-hydroxypregn-4en-3-one, and luteinizing hormone levels in superovulated prepuberal and postpuberal cattle. Biol. Reprod. 9:116–24
     [Google Scholar]
  19. 19. 
    Seidel GE Jr., Seidel SM. 1991. Training manual for bovine embryo transfer procedures Anim. Prod. Health Pap. 77 Food Agric. Organ. Rome:
  20. 20. 
    Seidel GE Jr. 1981. Superovulation and embryo transfer in cattle. Science 211:351–58
     [Google Scholar]
  21. 21. 
    Elsden RP, Hasler JF, Seidel GE Jr. 1976. Non-surgical recovery of bovine eggs. Theriogenology 6:523–32
     [Google Scholar]
  22. 22. 
    Glover MD, Seidel GE Jr. 2003. Increased messenger RNA for allograft inflammatory factor-1, LERK-5, and a novel gene in 17.5-day relative to 15.5-day bovine embryos. Biol. Reprod. 69:1002–12
     [Google Scholar]
  23. 23. 
    Viana J. 2020. 2019 statistics of embryo production and transfer in domestic farm animals. Int. Embryo Technol. Newsl. 38:7–26
     [Google Scholar]
  24. 24. 
    Elsden RP, Nelson LD, Seidel GE Jr. 1978. Superovulating cows with follicle stimulating hormone and pregnant mare's serum gonadotrophin. Theriogenology 9:17–26
     [Google Scholar]
  25. 25. 
    Williams TJ, Elsden RP, Seidel GE Jr. 1984. Pregnancy rates with bisected bovine embryos. Theriogenology 22:521–31
     [Google Scholar]
  26. 26. 
    Seidel GE Jr. 2002. Genetic and phenotypic similarity among members of mammalian clonal sets. Principles of Cloning J Cibelli, RP Lanza, KHS Campbell, MD West 215–25 London: Academic
     [Google Scholar]
  27. 27. 
    Takeda T, Elsden RP, Seidel GE Jr. 1987. Use of sucrose during removal of cryoprotectants after thawing eight-cell mouse embryos. Theriogenology 28:101–8
     [Google Scholar]
  28. 28. 
    Seidel GE Jr. 2006. Modifying oocytes and embryos to improve their cryopreservation. Theriogenology 65:228–35
     [Google Scholar]
  29. 29. 
    Horvath G, Seidel GE Jr. 2006. Vitrification of bovine oocytes after treatment with cholesterol-loaded methyl-β-cyclodextrin. Theriogenology 66:1026–33
     [Google Scholar]
  30. 30. 
    Seidel GE Jr. 1991. Embryo transfer: the next 100 years. Theriogenology 35:171–80
     [Google Scholar]
  31. 31. 
    Seidel GE Jr. 2014. Beef cattle in the year 2050. Adv. Exp. Med. Biol. 752:239–44
     [Google Scholar]
  32. 32. 
    Seidel GE Jr. 2018. Recreating extinct species. Proceedings of the 16th Technical Conference on Artificial Insemination and Reproduction81–85. Madison: Natl. Assoc. Anim. Breed.
     [Google Scholar]
  33. 33. 
    Seidel GE Jr. 2015. Lessons from reproductive technology research. Annu. Rev. Anim. Biosci. 3:467–87
     [Google Scholar]
  34. 34. 
    Seidel GE Jr., Foote RH. 1969. Influence of semen collection techniques on composition of bull seminal plasma. J. Dairy Sci. 52:1080–84
     [Google Scholar]
  35. 35. 
    Seidel GE Jr., Foote RH. 1969. Motion picture analysis of ejaculation in the bull. J. Reprod. Fertil. 20:313–17
     [Google Scholar]
  36. 36. 
    Seidel GE Jr., Foote RH. 1970. Compartmental analysis of sources of the bovine ejaculate. Biol. Reprod. 2:189–96
     [Google Scholar]
  37. 37. 
    Seidel GE Jr., Foote RH. 1973. Variance components of semen criteria from bulls ejaculated frequently and their use in experimental design. J. Dairy Sci. 56:399–405
     [Google Scholar]
  38. 38. 
    Chapman PL, Seidel GE Jr. 2008. Experimental design, power and sample size for animal reproduction experiments. Reprod. Fertil. Dev. 20:33–44
     [Google Scholar]
  39. 39. 
    Garner DL, Seidel GE Jr. 2008. History of commercializing sexed semen for cattle. Theriogenology 69:886–95
     [Google Scholar]
  40. 40. 
    Seidel GE Jr., Garner DL. 2002. Current status of sexing mammalian spermatozoa. Reproduction 124:733–43
     [Google Scholar]
  41. 41. 
    Seidel GE Jr., DeJarnette JM. 2021. Applications and world-wide use of sexed semen in cattle. Anim. Reprod. Sci. In press
    [Google Scholar]
  42. 42. 
    Deng JM, Satoh K, Wang H, Chang H, Zhang Z et al. 2011. Generation of viable male and female mice from two fathers. Biol. Reprod. 84:613–18
     [Google Scholar]
  43. 43. 
    Soller M. 2015. If a bull were a cow, how much milk would he give?. Annu. Rev. Anim. Biosci. 3:1–18
     [Google Scholar]
  44. 44. 
    Tian X. 2014. Genomic imprinting in farm animals. Annu. Rev. Anim. Biosci. 2:23–40
     [Google Scholar]
  45. 45. 
    Barker DJP. 2000. In utero programming of cardiovascular disease. Theriogenology 15:555–74
     [Google Scholar]
  46. 46. 
    Seidel GE Jr. 2010. Brief introduction to whole-genome selection in cattle using single nucleotide polymorphisms. Reprod. Fertil. Dev. 22:138–44
     [Google Scholar]
/content/journals/10.1146/annurev-animal-062521-090427
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Translating Basic Research to Animal Agriculture
Annual Review of Animal Biosciences 10, 1 (2022); https://doi.org/10.1146/annurev-animal-062521-090427
/content/journals/10.1146/annurev-animal-062521-090427
/content/journals/10.1146/annurev-animal-062521-090427
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  • Article Type: Review Article

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