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Annual Review of Pathology: Mechanisms of Disease

Volume 11, 2016

Mechanisms of Disease of Eosinophilic Esophagitis

Abstract

Eosinophilic esophagitis (EoE) is a recently recognized inflammatory disease of the esophagus with clinical symptoms derived from esophageal dysfunction. The etiology of EoE is now being elucidated, and food hypersensitivity is emerging as the central cornerstone of disease pathogenesis. Herein, we present a thorough picture of the current clinical, pathologic, and molecular understanding of the disease with a focus on disease mechanisms.

Keyword(s): atopy, barrier dysfunction, eosinophilic esophagitis, epithelial inflammation, fibrosis
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/content/journals/10.1146/annurev-pathol-012615-044241
2016-05-23
2024-05-01
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Mechanisms of Disease of Eosinophilic Esophagitis
Annual Review of Pathology: Mechanisms of Disease 11, 365 (2016); https://doi.org/10.1146/annurev-pathol-012615-044241
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